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Researchers decipher possible cause of Parkinson’s disease

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Misfolding and assembly of the alpha-synuclein protein in a nerve cell (image) is characteristic of Parkinson’s disease.

Why do people get Parkinson’s? The cause of the incurable disease is still unclear – now researchers from the University of Helsinki are one step closer to solving the mystery.

A research group led by Professor Per Saris aimed to investigate whether Desulfovibrio strains found in patients could lead to progression of Parkinson’s disease. And they found it.

“The results suggest that certain strains of Desulfovibrio bacteria are most likely to cause Parkinson’s disease,” Professor Per Saris said in a statement from the university.

Bacterial strains can be fought in the gut

Professor Saris says only a small portion of Parkinson’s disease — about 10 percent — is caused by single genes.

Saris: “Our results make it possible to trace carriers of these harmful Desulfovibrio bacteria. As a result, they can be targeted with measures to remove these strains from the gut, which can alleviate and slow the symptoms of Parkinson’s patients.”

Successful founding of Michael J. Fox

One of the most well-known Parkinson’s patients is US actor Michael J. Fox (61). The disease was diagnosed in 1991 in Fox, who was then 29 years old. “I’m not going to be 80,” he said in a recent interview with CBS.

Fox said he broke bones in his arms, elbows, hands and face as a result of multiple falls after undergoing tumor surgery on his spine. Falls are a common cause of death in people with Parkinson’s.

The Parkinson’s Foundation initiated and co-funded a study that showed that detecting a protein in the cerebrospinal fluid allows diagnosis of Parkinson’s disease long before the onset of the disease. (what is that)

Source : Blick

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