LSD works against depression

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Swiss chemist Albert Hofmann accidentally discovered the intoxicating effects of LSD on April 16, 1943, while searching for new drugs in his Basel laboratory.

For the study, 61 patients were treated with low or moderate to high doses of LSD. Patients and therapists did not know who was in which group (randomised, double-blind, parallel group study). For treatment, patients received the respective doses of LSD twice at four-week intervals.

The study was led by the US biopharmaceutical company MindMed and Matthias Liechti, Felix Müller and colleagues from the University of Basel.

works harder

Müller said that administering 100 or 200 micrograms of LSD reduced depressive symptoms two weeks and three months after treatment. His conclusion: “Two medium- and high-dose LSDs significantly reduced depressive symptoms compared to two low-dose LSDs.” The study has not yet been reviewed by independent experts and has not been published in a specialist journal.

Decades ago, there was research showing that LSD was effective in treating depression, but it wasn’t conducted under today’s harsh conditions. Liechti and Müller wanted to test the results of that time. Research has stalled as LSD has been abused as a recreational drug, discredited and banned. It has been gaining momentum again for several years. (SDA)

Study: https://doi.org/10.1016/j.biopsych.2022.08.025

Source : Blick