Corona drug Remdesivir had a positive effect

According to a new study conducted in Switzerland, the corona drug Remdesivir reduces the death rate by about two percent. However, only in patients who do not have conventional oxygen therapy or who only receive conventional oxygen therapy. The results are in the expert journal “Lancet Respiratory Medicine” seen.

When it comes to the patients most severely affected by the coronavirus – so-called High Flow Oxygen Therapy necessary – however, scientists from the University of Basel and University Hospital Basel explained. This may be related to the fact that very little data is available about this group of affected people.

However, the researchers were unable to detect any adverse effects of the drug in patients with a critical Covid 19 infection. “Fortunately, we found that remdesivir did not cause any more serious side effects compared to regular treatment,” said lead author Benjamin. memory A statement from the University of Basel on Wednesday.

Data from more than 10,000 unvaccinated people

Originally developed against the Ebola virus, Remdesivir was one of the first drugs approved for the treatment of Covid-19 in Switzerland in 2020. Since then, several international studies have examined how remdesivir treatment affects the mortality rate in adults hospitalized with Covid-19. The results were conflicting and therefore how well the drug worked and whether its benefit differed in individual patient groups remained controversial.

The researchers have now collected and reanalyzed individual patient data from eight clinical studies. This is data from more than 10,000 unvaccinated patients from more than 40 countries. hospital He had been treated for Covid-19. The results are in line with current WHO guidelines recommending the use of remdesivir for patients with severe but non-critical Covid-19 infection.

With regard to age, the presence of concomitant diseases or subgroups There was no evidence of a differential benefit of the active substance for patients with different levels of inflammation markers. In addition, remdesivir treatment did not lead to an earlier treatment. discharge from hospital. The study said the effect of remdesivir in people who have been vaccinated or who have recovered needs to be clarified in further research. (SDA)

Source :Blick